Novel semi-synthetic 7-hydroxymitragynine products pose public health risks due to the unknown chemical constituents and the known pharmacology of 7-hydroxymitragynine. Clinicians must screen patients for their use and policymakers must distinguish between kratom and 7-hydroxymitragynine.
The policy implications of semi-synthetic 7-hydroxymitraynine products are unknown, but adverse events or fatalities resulting from 7-hydroxymitragynine products could pose complications to the regulation of a growing kratom industry. Kratom is now used by 10–15 million US adults. Decisions regarding kratom scheduling and regulation are liable to become confused if policymakers can or will not differentiate between kratom and high-potency 7-hydroxymitragynine products synthesized in unregulated or makeshift laboratories. To be clear: equating 7-hdyroxymitragynine products to kratom is analogous to equating synthetic cannabinoids to unaltered cannabis or hemp. Although not all organic kratom products are equal, they have not emerged as a net detriment to public health, and they remain unscheduled at the federal level. Novel semi-synthetic 7-hydroxymitragynine products pose public health risks due to the unknown chemical constituents and the known pharmacology of 7-hydroxymitragynine. Clinicians must screen patients for their use and policymakers must distinguish between kratom and 7-hydroxymitragynine.
The Scientific Association for Botanical Education and Research (SABER) is sounding the alarm over the public health risks associated with products labeled as 7-hydroxymitragynine (7-OH). These products, often falsely marketed as kratom leaf extracts, are synthetically produced and pose significant dangers, according to the association.
"Synthetic 7-OH is not kratom—it is a highly potent, unregulated chemical," said Professor Paula Brown of the BC Institute of Technology. "Consumers have a right to transparency, yet these products are often mislabeled and marketed deceptively as natural extracts. Without proper quality and safety testing, they carry a significant risk of causing harm."
Police say the teenager called 911 before the shooting and told dispatch he was going to kill himself or someone else, then hung up, the outlet reported. When the dispatcher called back, the teen’s mother answered and said there was nothing happening at the home, according to police.
Police “found that the 15-year-old suspect had just eaten a bunch of edibles, and I guess had a bad reaction to them,” Horelica told the station.
Kratom has addictive properties and can be dangerous to use. The Poison Information Centre reports that several people in Sweden have sought medical attention after ingesting kratom. There are also several cases, according to the National Board of Forensic Medicine, where mitragynin has contributed to death or been the cause of death, writes FHM in a press release.
Hemp Gazetter- Since that time, support for legalization seems to have dropped off a little according to a recent Florida Chamber of Commerce poll, conducted February 2 – 8, 2025 among 600 likely voters statewide. It found 53% supported legalization, the sixth consecutive poll the Chamber has carried out indicating less than 60% threshold required for passage.
The Chamber notes the result comes despite more than USD $150 million being spent to try and pass the amendment during the 2024 election.
Kratom is a plant from Southeast Asia that contains the narcotic-classified substance mitragynin, which poses health risks when used and can cause death.
In 2023, according to the Customs Agency, over 40 tons of kratom were imported into Sweden. It is sold as a plant powder in some kiosks and web shops.
Kratom produces mild stimulating and euphoric effects at low doses, while larger doses produce opioid-like effects.
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